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Product Information:

VU0364572

VU0364572 is a potent, orally bioavailable and CNS penetrant M1 agonist with high selectivity, clean ancillary pharmacology and enantiospecific activity.

Cat. No.: EX-A7805    Purity: >98%
Chemical
Chemical structure of VU0364572


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500In-stock
100mg800In-stock
200mg1285In-stock
500mg2285In-stock


CAS No.1240514-87-7
Purity>98%
FormulaC21H31N3O3
Mol Weight373.4891
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lebois, Evan P et al. “Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071.” Bioorganic & medicinal chemistry letters vol. 21,21 (2011): 6451-5.

[2]. Digby, Gregory J et al. “Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.” The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 32,25 (2012): 8532-44.

CoACoA of VU0364572
Smiles:O=C(OCC)N1CCC(CC1)N2C[C@@H](CCC2)NC(C3=CC=CC=C3C)=O

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