VU0364572 TFA

VU0364572 is a potent, orally bioavailable and CNS penetrant M1 agonist with high selectivity, clean ancillary pharmacology and enantiospecific activity.


Cat. No.: EX-A7805A	Purity: >98%

	Chemical structure of VU0364572 TFA

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	485	In-stock
100mg	785	In-stock
200mg	1285	In-stock
500mg	2285	In-stock

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CAS No.	1240514-89-9
Purity	>98%
Formula	C23H32F3N3O5
Mol Weight	487.5125
Color	White to off-white
State	solid powder
Solubility	DMSO : 55 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lebois, Evan P et al. “Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071.” Bioorganic & medicinal chemistry letters vol. 21,21 (2011): 6451-5. [2]. Digby, Gregory J et al. “Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.” The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 32,25 (2012): 8532-44.
CoA	CoA of VU0364572 TFA

Smiles:	O=C(N1CCC(N2C[C@H](NC(C3=CC=CC=C3C)=O)CCC2)CC1)OCC.O=C(O)C(F)(F)F


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