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Product Information:

VTX-2337

Motolimod (VTX-2337) is a selective Toll-like receptor 8 (TLR8) agonist, with an EC50 of approximately 100 nM.

Cat. No.: EX-A1102    Purity: >98%
Chemical
Chemical structure of VTX-2337


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg825In-stock
1g1198In-stock


SynonymsMotolimod
CAS No.926927-61-9
Purity>98%
FormulaC28H34N4O2
Mol Weight458.5952
Colorlight yellow to brown
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lu H, et al. VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC. Clin Cancer Res. 2012 Jan 15;18(2):499-509.

[2]. Dietsch GN, et al. Coordinated Activation of Toll-Like Receptor8 (TLR8) and NLRP3 by the TLR8 Agonist, VTX-2337, Ignites Tumoricidal Natural Killer Cell Activity. PLoS One. 2016 Feb 29;11(2):e0148764.

CoACoA of VTX-2337
Smiles:CCCN(CCC)C(=O)C1=CC2=CC=C(C=C2N=C(N)C1)C1=CC=C(C=C1)C(=O)N1CCCC1

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