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Product Information:

VT-1598 TsOH salt

VT-1598 tosylate is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 tosylate shows anti-fungal activity against Candida auris. VT-1598 tosylate is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.: EX-A7312A    Purity: >98%
Chemical
Chemical structure of VT-1598 TsOH salt


For research only, Do not use for Human!

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25mg880In-stock
100mg2400In-stock
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CAS No.2089321-00-4
Purity>98%
FormulaC38H28F4N6O5S
Mol Weight756.725
 
 
Reference:  

[1]. Nathan P Wiederhold, et al. The Fungal Cyp51-Specific Inhibitor VT-1598 Demonstrates In Vitro and In Vivo Activity against Candida auris. Antimicrob Agents Chemother. 2019 Feb 26;63(3):e02233-18.

[2]. Timothy J Break, et al. VT-1598 inhibits the in vitro growth of mucosal Candida strains and protects against fluconazole-susceptible and -resistant oral candidiasis in IL-17 signalling-deficient mice. J Antimicrob Chemother. 2018 Aug 1;73(8):2089-2094.

CoACoA of VT-1598 TsOH salt

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