VT-105

VT-105 is a potent and selective TEAD Auto-palmitoylation inhibitor that Inhibits Proliferation and Tumor Growth of NF2-deficient Mesothelioma. VT105 is a more soluble analog of VT104.


Cat. No.: EX-A5850	Purity: >99%

	Chemical structure of VT-105

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	510	in_stock
10mg	670	in_stock
50mg	1214	in_stock
100mg	1643	in_stock
250mg	2161	in_stock
500mg	2745	in_stock

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CAS No.	2417718-38-6
Purity	>99%
Formula	C24H18F3N3O
Mol Weight	421.4144
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO: ? 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tang TT, Konradi AW, Feng Y, Peng X, Ma M, Li J, Yu FX, Guan KL, Post L. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021 Jun;20(6):986-998. doi: 10.1158/1535-7163.MCT-20-0717. Epub 2021 Apr 13. PMID: 33850002.
Data Sheet	Data sheet of VT-105
CoA	CoA of VT-105
SDS	SDS of VT-105

Smiles:	O=C(C1=CC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2N=C1)N[C@H](C4=NC=CC=C4)C


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