VS-4718

PND-1186 (VS-4718, SR-2156) is a reversible and selective FAK inhibitor with IC50 of 1.5 nM. PND-1186 (VS-4718) selectively promotes tumor cell apoptosis.


Cat. No.: EX-A505	Purity: >98%

	Chemical structure of VS-4718

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	295	in_stock
1g	587	in_stock
2g	924	in_stock
3g	1098	in_stock
5g	1436	in_stock
10g	2345	in_stock

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Synonyms	PND1186
Synonyms 2	SR-2516
CAS No.	1061353-68-1
Purity	>98%
Formula	C25H26F3N5O3
Mol Weight	501.5008
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tanjoni, Isabelle et al. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. Cancer biology & therapy vol. 9,10 (2010): 764-77.
CoA	CoA of VS-4718

Smiles:	CNC(=O)C1=CC=CC=C1NC1=CC(NC2=CC=C(C=C2OC)N2CCOCC2)=NC=C1C(F)(F)F


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