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Product Information:

Vizenpistat

Vizenpistat is an ENPP1 inhibitor that can be used in the study of cancer .

Cat. No.: EX-A15527    Purity: >98%
Chemical
Chemical structure of Vizenpistat


For research only, Do not use for Human!

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SynonymsSR-8541A
CAS No.2687222-58-6
Purity>98%
FormulaC15H21N5O4S
Mol Weight367.423
ColorWhite to off-white
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kaadige M.R., et al. Abstract CT200: Phase I dose-escalation study of ENPP1 inhibitor, vizenpistat, for the treatment of solid tumors. Cancer Research, 2026, 86(8_Supplement): CT200.

[2]. Larsen A.S., et al. Abstract CT221: A progress report for a Phase 1b/2 study of ENPP1 inhibitor, vizenpistat in combination with botensilimab and balstilimab in subjects with refractory metastatic microsatellite stable colorectal cancer. Cancer Research, 2026, 86(8_Supplement): CT221.

[3]. Weston A., et al. Inhibition of ENPP1 using small molecule, SR-85411A, enhances the effect of checkpoint inhibition in cancer models.

[4]. Weston A., et al. SR-85411A is a potent inhibitor of ENPP1 and exhibits dendritic cell mediated anti-tumor activity.

CoACoA of Vizenpistat
Smiles:O=S(N)(N1CCN(CCC1)C2=C3C=C(OC)C(OC)=CC3=NC=N2)=O

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