VISTA-IN-3

VISTA-IN-3 (Compound A4) is a potent VISTA small molecule inhibitor with a KD value of 0.49 μM. VISTA-IN-3 can induce the release of IFN-γ cytokines. VISTA-IN-3 synergistically enhances anti-cancer activity with PD-L1 antibody.


Cat. No.: EX-A16975	Purity: >98%

	Chemical structure of VISTA-IN-3

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	553	in_stock
100mg	740	in_stock
250mg	1069	in_stock
500mg	1478	in_stock
1g	2047	in_stock

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CAS No.	2994662-45-0
Purity	>98%
Formula	C14H18N4O3
Mol Weight	290.3177
Color	White to off-white
State	Solid
Solubility	DMSO : 6.25 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sun C, He Y, et al. Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors. J Med Chem. 2024 Feb 27.
CoA	CoA of VISTA-IN-3

Smiles:	OC1=CC=CC(NC2=NC(OC)=CC(CNCCO)=N2)=C1


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