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Product Information:

Vicriviroc

Vicriviroc(SCH-417690) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, and also inhibits HIV-1 in PBMC cells.

Cat. No.: EX-A4709A    Purity: >98%
Chemical
Chemical structure of Vicriviroc


For research only, Do not use for Human!

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SynonymsSCH-D
CAS No.306296-47-9
Purity>98%
FormulaC28H38F3N5O2
Mol Weight533.6288
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Tagat JR, et al. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. J Med Chem. 2004 May 6;47(10):2405-8.
CoACoA of Vicriviroc
Smiles:C[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C

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