Vemtoberant

Vemtoberant is a β3-adrenergic receptor inhibitor with a human Ki of 8.2 nM, and exhibits 400- to 600-fold selectivity over human β1-AR and β2-AR. Vemtoberant attenuates β3-AR-mediated cardiac inhibition. Vemtoberant can be used for the research of systolic heart failure .


Cat. No.: EX-A7995	Purity: >98%

	Chemical structure of Vemtoberant

For research only, Do not use for Human!

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CAS No.	2169905-68-2
Purity	>98%
Formula	C29H37N3O8S2
Mol Weight	619.749
Color	Off-white to light yellow
State	solid powder
Solubility	DMSO : 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Sabbah HN, et al. Intravenous Infusion of the β₃-Adrenergic Receptor Antagonist APD418 Improves Left Ventricular Systolic Function in Dogs With Systolic Heart Failure. J Card Fail. 2021;27(2):242-252.
CoA	CoA of Vemtoberant

Smiles:	CCN1C=C(C(=O)C2=CC=CC=C21)S(=O)(=O)N3CCC4(CC3)C[C@H](CO4)NC[C@@H](COC5=CC(=CC=C5)S(=O)(=O)C)O


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