VEGFR-2-IN-61

VEGFR-2-IN-61 (Compound 7b) is an inhibitor for VEGFR-2 with an IC50 of 2.83 µM. VEGFR-2-IN-61 inhibits the proliferation of multi cancer cells (IC50 for MCF-7 is 2.12 μM). VEGFR-2-IN-61 inhibits the cell migration, induces oxidative stress and apoptosis in MCF-7.


Cat. No.: EX-A13005	Purity: >98%

	Chemical structure of VEGFR-2-IN-61

For research only, Do not use for Human!

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CAS No.	3068991-90-9
Purity	>98%
Formula	C27H25N5O
Mol Weight	435.5203
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Valapil DG, et al., Development of 3-indolyl substituted phenyl pyrazolo-carboxamide hybrids as potential type II VEGFR-2 inhibitors and in vitro cytotoxicity studies. Bioorg Med Chem Lett. 2025 Mar 1;117:130070.
CoA	CoA of VEGFR-2-IN-61

Smiles:	O=C(NC1=CC=C(C=C1)C(C)C)C=2C(=NN(C=3C=CC=CC3)C2N)C4=CNC=5C=CC=CC54


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