VAV1 degrader-4

VAV1 degrader-4 is a VAV1 molecular glue degrader with a DC50 value of 3.93 nM for VAV1 in Jurkat cells. VAV1 degrader-4 can dose-dependently inhibit the production of IL-2. VAV1 degrader-4 can be used for research on autoimmune diseases .


Cat. No.: EX-A17465	Purity: >98%

	Chemical structure of VAV1 degrader-4

For research only, Do not use for Human!

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CAS No.	3119457-09-6
Purity	>98%
Formula	C23H17ClF2N2O4
Mol Weight	458.842

Reference:	[1].Zhang XJ, et al. VAV1 degrading agent. China, CN 121735906. 2025-09-25.
CoA	CoA of VAV1 degrader-4

Smiles:	O=C1NC(=O)C(C2=CC=CC(C3=CC=C(C=C3)N4C=CC=C(OC(F)F)C4=O)=C2Cl)CC1


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