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Product Information:

USP25 and 28 inhibitor AZ2

USP25/28-IN-2 is a selectivity dual USP25/28 inhibitor with IC50 values of 0.88 and 1.1 μM, respectively. USP25/28-IN-2 modulates USP25 and USP28 activity to affect downstream pathways, modulates c-Myc oncoprotein total levels and half-life, induces apoptosis, reduces cell viability. USP25/28-IN-2 can be used for the research of colorectal carcinoma, colorectal adenocarcinoma.

Cat. No.: EX-A7133    Purity: >98%
Chemical
Chemical structure of USP25 and 28 inhibitor AZ2


For research only, Do not use for Human!

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SynonymsUSP25/28 inhibitor AZ-2
Synonyms 2USP25/28-IN-AZ2
CAS No.2165322-95-0
Purity>98%
FormulaC17H17BrF3NO3
Mol Weight420.221
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wrigley JD, et al. Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily. ACS Chem Biol. 2017;12(12):3113-3125.

CoACoA of USP25 and 28 inhibitor AZ2

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