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Product Information:

URAT1 inhibitor 7

URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC50 of 12 nM. URAT1 inhibitor 7 exhibits microsomal stability (HLM <13 µL/min/mg). URAT1 inhibitor 7 also inhibits CYP2C9, with an IC50 of 4.2 μM. URAT1 inhibitor 7 can be used for gout research.

Cat. No.: EX-A7945H    Purity: >98%
Chemical
Chemical structure of URAT1 inhibitor 7


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg495In-stock
10mg695In-stock
25mg1085In-stock
200mg2285In-stock


CAS No.1632002-28-8
Purity>98%
FormulaC19H10ClFN4O3S
Mol Weight428.824
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 25 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years ; In solvent    -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Storer R I, et al. The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout. MedChemComm, 2016:10.1039.C6MD00190D.

CoACoA of URAT1 inhibitor 7

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