UC-514321

UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity .


Cat. No.: EX-A15170	Purity: >98%

	Chemical structure of UC-514321

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	522	In-stock
100mg	786	In-stock
250mg	1325	In-stock
500mg	2348	In-stock
1g	get quote	In-stock

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CAS No.	299420-83-0
Purity	>98%
Formula	C26H35NO5
Mol Weight	441.5598
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 year;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Jiang X, et al. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nat Commun. 2017 Dec 13;8(1):2099.
CoA	CoA of UC-514321

Smiles:	OC1=C(C=C2OCOC2=C1)C(N3CCOCC3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O


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