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Tubulin polymerization-IN-93

Tubulin polymerization-IN-93 is a β-tubulin polymerization inhibitor. Tubulin polymerization-IN-93 disrupts the microtubule network structure. Tubulin polymerization-IN-93 activates the spindle assembly checkpoint and promotes Mitotic catastrophe. Tubulin polymerization-IN-93 activates the mitochondrial Apoptotic pathway. Tubulin polymerization-IN-93 exhibits anticancer activity against acute myeloid leukemia .

Cat. No.: EX-A17402    Purity: >98%
Chemical
Chemical structure of Tubulin polymerization-IN-93


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg485Inquire
10mg685Inquire
25mg1085Inquire


CAS No.3022872-60-9
Purity>98%
FormulaC22H23NO6
Mol Weight397.4211
 
 
Reference:  

[1].Tan P, et al. Discovery of furan-trimethoxyphenyl hybrids as novel colchicine-binding site inhibitors that induce mitotic catastrophe with potent anti-acute myeloid leukemia effect. Bioorganic chemistry. 2026 Jun 16;180:110109.

CoACoA of Tubulin polymerization-IN-93
Smiles:COC1=CC(N(C(C2=CC=CO2)=O)CC3=CC=C(OC)C=C3)=CC(OC)=C1OC

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