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Tubulin polymerization-IN-63

Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research.

Cat. No.: EX-A13359    Purity: >98%
Chemical
Chemical structure of Tubulin polymerization-IN-63


For research only, Do not use for Human!

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CAS No.3040385-73-4
Purity>98%
FormulaC20H24ClCuN5O2S
Mol Weight497.501
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Milunovic MNM, et al. Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubulin Polymerization: The Morpholine Position Matters. J Med Chem. 2024 Jun 13;67(11):9069-9090.

CoACoA of Tubulin polymerization-IN-63
Smiles:Cl[Cu]12([N]3(C4)CCOCC3)[N](N=C(NC5=CC(C)=C(O)C(C)=C5)S2)=CC6=CC=CC4=[N]61

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