Trovirdine

Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate. IC50 value: 7 nM Target: HIV-1 Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.


Cat. No.: EX-A14794	Purity: >98%

	Chemical structure of Trovirdine

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	472	In-stock
500mg	658	In-stock
1g	950	In-stock
2g	1556	In-stock
5g	2968	In-stock

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Synonyms	LY300046
CAS No.	149488-17-5
Purity	>98%
Formula	C13H13BrN4S
Mol Weight	337.238
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 year;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127. [2]. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.
CoA	CoA of Trovirdine

Smiles:	C1=CC=NC(=C1)CCNC(=S)NC2=NC=C(C=C2)Br


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