Tri-valent linker-3

Tri-valent linker-3 is a linker targeting Polymyxin B (PMB) and can be used to synthesize PMB-based drug delivery systems. Polymyxin B carries molecular payloads (e.g., nucleic acid agents) through the linker and binds megalin (a cell surface factor on the surface of target cells) with high affinity, thereby delivering the payload to tissues or cells.


Cat. No.: EX-A13290	Purity: >98%

	Chemical structure of Tri-valent linker-3

For research only, Do not use for Human!

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CAS No.	3080635-27-1
Purity	>98%
Formula	C88H140N8O31
Mol Weight	1806.0883
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lawrence Jonathan, et al. Polymyxins for delivery of agents to the kidney. World Intellectual Property Organization, WO2025072713 A1. 2025-04-03.
CoA	CoA of Tri-valent linker-3

Smiles:	O=C(CCC1=O)N1OC(CCOCCOCCOCCOCCOCCC(NC(COCCC(NCCOCCOCCOCCNC(OC[C@H]2[C@]3([H])[C@@]2([H])CCC#CCC3)=O)=O)(COCCC(NCCOCCOCCOCCNC(OC[C@H]4[C@]5([H])[C@@]4([H])CCC#CCC5)=O)=O)COCCC(NCCOCCOCCOCCNC(OC[C@H]6[C@]7([H])[C@@]6([H])CCC#CCC7)=O)=O)=O)=O


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