Trastuzumab emtansine

Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine). Trastuzumab emtansine can be used for the research of advanced breast cancer.


Cat. No.: EX-A7227	Purity: >98%

	Chemical structure of Trastuzumab emtansine

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	3880	In-stock
50mg	5906	In-stock
100mg	9845	In-stock
250mg	15800	Inquire

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Synonyms	Trastuzumab-MCC-DM 1
Synonyms 2	Ado-trastuzumab emtansine
CAS No.	1018448-65-1
Purity	>98%
Formula	C6448H9948N1720O2012S44·(C47H62ClN4O13S)n
Color	White to off-white
State	liquid
Shelf Life	>2 years if stored properly
Storage	Liquid -20℃ 2 years
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Ice bag + foam box available upon request. Dry ice + foam box available upon request.

Reference:	[1]. Verma S, et, al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med. 2012 Nov 8;367(19):1783-91. [2]. Menderes G, et, al. Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression. Gynecol Oncol. 2017 Oct;147(1):145-152.
CoA	CoA of Trastuzumab emtansine


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