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Product Information:

trans-AUCB

trans-AUCB (t-AUCB) is a potent, orally active and selective soluble epoxide hydrolase (sEH) inhibitor with IC50s of 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively. trans-AUCB has anti-glioma activity.

Cat. No.: EX-A7729    Purity: >98%
Chemical
Chemical structure of trans-AUCB


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg785In-stock
100mg1150In-stock
250mg1750In-stock


Synonymst-AUCB
CAS No.885012-33-9
Purity>98%
FormulaC24H32N2O4
Mol Weight412.5219
Appearancewhite to off-white powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li J, et al. t-AUCB, an improved sEH inhibitor, suppresses human glioblastoma cell growth by activatingNF-κB-p65. J Neurooncol. 2012 Jul;108(3):385-93.

[2]. Liu JY, et al. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murinemodel of inflammation. Br J Pharmacol. 2009 Jan;156(2):284-96.

CoACoA of trans-AUCB

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