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Product Information:

TR-107

Anticancer agent 230 (example 65) is a caseinolytic protease P (ClpP) activator with anticancer activity. Anticancer agent 230 is able to induce the degradation of mitochondrial proteins in SUM159 and MDA-MB-231 triple-negative breast cancer cells in a time-dependent manner .

Cat. No.: EX-A16474    Purity: >98%
Chemical
Chemical structure of TR-107


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg360In-stock
500mg560In-stock
1g920In-stock
2g1450In-stock
3g1750In-stock
5g2300In-stock


CAS No.2485052-87-5
Purity>98%
FormulaC22H19ClN4O
Mol Weight390.865
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Preparation of tetrahydropyrido[4,3-d]pyrimidine-2,4-dione analogs useful in the treatment of cancers and in modulating the activity of caseinolytic protease p function. United States, US20230339947 A1. 2023-10-26.

CoACoA of TR-107
Smiles:C1CN(CC2=C1N=CN(C2=O)CC3=CC=C(C=C3)Cl)CC4=CC(=CC=C4)C#N

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