Tovinontrine

Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease. IC50s are 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively.


Cat. No.: EX-A5357	Purity: >98%

	Chemical structure of Tovinontrine

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
10mg	985	In-stock
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Synonyms	IMR-687
CAS No.	2062661-53-2
Purity	>98%
Formula	C21H26N6O2
Mol Weight	394.4701
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. James G McArthur, et al. A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease. Haematologica. 2020 Mar;105(3):623-631.
CoA	CoA of Tovinontrine


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