Topoisomerase I inhibitor 8

Topoisomerase I inhibitor 8 is a potent topoisomerase I inhibitor. Topoisomerase I inhibitor 8 is a hexacyclic analogue of camptothecin, and displays cytotoxic effect against tumor cells.


Cat. No.: EX-A11312	Purity: >98%

	Chemical structure of Topoisomerase I inhibitor 8

For research only, Do not use for Human!

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CAS No.	210346-40-0
Purity	>98%
Formula	C24H21FN2O4
Mol Weight	420.4329
Color	Light yellow to brown
State	solid
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sugimori M, et al. Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues. J Med Chem. 1998 Jun 18;41(13):2308-18.
CoA	CoA of Topoisomerase I inhibitor 8

Smiles:	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5CCCC6=C5C(=CC(=C6C)F)N=C4C3=C2)O


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