Topo I-IN-1

Topo I-IN-1 (Compound 14d) is a potent Topo I inhibitor with antitumor activity and DNA intercalative capability. Topo I-IN-1 induces cell apoptosis.


Cat. No.: EX-A12921	Purity: >98%

	Chemical structure of Topo I-IN-1

For research only, Do not use for Human!

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CAS No.	2763655-68-9
Purity	>98%
Formula	C20H14BrN3O2
Mol Weight	408.248

Reference:	[1]. Manasa Kadagathur, et al. Synthesis of indolo/pyrroloazepinone-oxindoles as potential cytotoxic, DNA-intercalating and Topo I inhibitors. Bioorg Chem. 2022 May;122:105706.
CoA	CoA of Topo I-IN-1

Smiles:	O=C1C2=C(/C(/CCN1)=C\3/C=4C(NC3=O)=CC(Br)=CC4)C=5C(N2)=CC=CC5


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