TNIK inhibitor OBD9

TNIK inhibitor OBD9 is a small molecule TNIK inhibitor that blocks Wnt/beta-catenin signaling at the final step of transcriptional activation, suppresses colorectal cancer growth by interfering with the Wnt signaling pathway.


Cat. No.: EX-A10313	Purity: >98%

	Chemical structure of TNIK inhibitor OBD9

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	485	In-stock
10mg	685	In-stock
25mg	1085	In-stock
50mg	get quote	In-stock
100mg	get quote	In-stock
250mg	get quote	In-stock

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Synonyms	Tubulin-IN-52
Synonyms 2	OBD9
CAS No.	2099064-75-0
Purity	>98%
Formula	C20H20N4O4
Mol Weight	380.3972
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhou, Kun et al. “Inhibition of Wnt Signaling in Colon Cancer Cells via an Oral Drug that Facilitates TNIK Degradation.” Molecular cancer therapeutics vol. 22,1 (2023): 25-36. doi:10.1158/1535-7163.MCT-21-0801 [2]. Cheong, Jae Eun et al. “Synthesis and anticancer activity of novel water soluble benzimidazole carbamates.” European journal of medicinal chemistry vol. 144 (2018): 372-385. doi:10.1016/j.ejmech.2017.11.037
CoA	CoA of TNIK inhibitor OBD9

Smiles:	O=C(OC)NC1=NC=2C=CC(=CC2N1)C(=O)C3=CC=C(C=C3)N(C)C4COC4


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