TMX-4140

TMX-4140 is a selective PIP4K2C inhibitor with a KD of 7.2 nM for PIP4K2C over PIP4K2B. TMX-4140 can be used for synthesis of PROTAC TMX-4153 (HY-153119) .


Cat. No.: EX-A16259	Purity: >98%

	Chemical structure of TMX-4140

For research only, Do not use for Human!

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1g	get quote	inquire
5g	get quote	inquire

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CAS No.	2867519-51-3
Purity	>98%
Formula	C25H20ClN5O
Mol Weight	441.912
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Teng M, et al. Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader. Angew Chem Int Ed Engl. 2023 Apr 24;62(18):e202302364.
CoA	CoA of TMX-4140

Smiles:	O=C1N(C=2C=NC=C(C2)NC3=NC=C(Cl)C(=N3)C=4C=CC=C(C4)C=5C=CC=CC5)CCC1


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