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Product Information:

TLR7-8 agonist 1 dihydrochloride

TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline.

Cat. No.: EX-A5391    Purity: >98%
Chemical
Chemical structure of TLR7-8 agonist 1 dihydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg385In-stock
250mg585In-stock
500mg785In-stock
1g1185In-stock
5g3885In-stock


SynonymsTLR7/8 agonist 1 dihydrochloride
CAS No.1620278-72-9
Purity>98%
FormulaC22H27Cl2N5
Mol Weight432.389
ColorOff-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO 83.33 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Shukla NM, et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6384-6.

[2]. Beesu M, et al. Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity. J Med Chem. 2015 Oct 8;58(19):7833-49.
CoACoA of TLR7-8 agonist 1 dihydrochloride

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