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Product Information:

tilivalline

Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC).

Cat. No.: EX-A12351    Purity: >98%
Chemical
Chemical structure of tilivalline


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg410In-stock
10mg650In-stock
25mg1280In-stock
50mg2050In-stock
100mg3340In-stock
250mg6700In-stock


CAS No.80279-24-9
Purity>98%
FormulaC20H19N3O2
Mol Weight333.3838
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hering NA, et al. Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment. Int J Mol Sci. 2019 Nov 8;20(22):5595.

[2]. von Tesmar A, et al. Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development. ACS Chem Biol. 2018 Mar 16;13(3):812-819.

CoACoA of tilivalline
Smiles:O=C1N2[C@]([C@@H](NC=3C1=CC=CC3O)C=4C=5C(NC4)=CC=CC5)(CCC2)[H]

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