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Product Information:

Tie2 kinase inhibitor 1

Tie2 kinase inhibitor 1 (compound 5) is a potent, selective Tie2 kinase inhibitor with an IC50 of 250 nM. Tie2 kinase inhibitor 1 has anti-cancer activity.

Cat. No.: EX-A7310    Purity: >98%
Chemical
Chemical structure of Tie2 kinase inhibitor 1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg1085In-stock
250mg1685In-stock


CAS No.948557-43-5
Purity>98%
FormulaC26H21N3O2S
Mol Weight439.529
ColorLight yellow to yellow
Statesolid powder
SolubilityDMSO : 17.86 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 year
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Semones M, et al. Pyridinylimidazole inhibitors of Tie2 kinase. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4756-60. Epub 2007 Jun 27.

[2]. Hasenstein JR, et al. Efficacy of Tie2 receptor antagonism in angiosarcoma. Neoplasia. 2012 Feb;14(2):131-40.

CoACoA of Tie2 kinase inhibitor 1

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