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Product Information:

Ticagrelor

Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.

Cat. No.: EX-A503    Purity: >99.5%
Chemical
Chemical structure of Ticagrelor


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg250In-stock
250mg300In-stock
500mg350In-stock
1g450In-stock
5g885In-stock
10g1485In-stock


SynonymsAZD6140
CAS No.274693-27-5
Purity>99.5%
FormulaC23H28F2N6O4S
Mol Weight522.568
Coloroff-white to yellow
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month; protect from light, stored under nitrogen
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Aungraheeta R, et al. Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor. Blood. 2016 Dec 8;128(23):2717-2728.

[2]. Gebremeskel S, et al. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015 Jan 1;136(1):234-40.

[3]. Sugidachi A, et al. A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats. Br J Pharmacol. 2013 May;169(1):82-9.

CoACoA of Ticagrelor
Smiles:CCCSC1=NC(N[C@@H]2C[C@H]2C2=CC=C(F)C(F)=C2)=C2N=NN([C@@H]3C[C@H](OCCO)[C@@H](O)[C@H]3O)C2=N1

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