Thalidomide-5-NH-PEG1-NH2 hydrochloride

Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide -based cereblon ligand that recruits CRBN proteins. Thalidomide-5-NH-PEG1-NH2 hydrochloride can be connected to the target protein ligand through a linker to form a PROTAC molecule. For example, THAL-SNS-032.


Cat. No.: EX-A10497	Purity: >98%

	Chemical structure of Thalidomide-5-NH-PEG1-NH2 hydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
1g	1050	In-stock
5g	get quote	In-stock

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CAS No.	2863634-98-2
Purity	>98%
Formula	C17H21ClN4O5
Mol Weight	396.825
Color	Light yellow to brown
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture and light; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53. [Content Brief]
CoA	CoA of Thalidomide-5-NH-PEG1-NH2 hydrochloride

Smiles:	O=C1NC(C(CC1)N2C(C3=CC=C(NCCOCCN)C=C3C2=O)=O)=O.Cl


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