THAL-SNS-032

THAL-SNS-032 is a selective CDK9 degrader PROTAC composed of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN).


Cat. No.: EX-A4457	Purity: >98%

	Chemical structure of THAL-SNS-032

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	625	In-stock
250mg	1100	In-stock
500mg	1600	In-stock
1g	2250	In-stock
2g	3600	In-stock
5g	7800	In-stock

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CAS No.	2139287-33-3
Purity	>98%
Formula	C40H52N8O10S2
Mol Weight	869.018
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Olson CM，et al. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation. Nat Chem Biol. 2018 Feb;14(2):163-170.
CoA	CoA of THAL-SNS-032

Smiles:	O=C(NCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN4CCC(C(NC5=NC=C(SCC6=NC=C(C(C)(C)C)O6)S5)=O)CC4


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