TERT activator-1

TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). TERT activator-1 promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. TERT activator-1 promotes adult neurogenesis and enhances neuromuscular function. TERT activator-1 reduces cellular senescence and systemic inflammation in aged mice, and can be used in the study of aging.


Cat. No.: EX-A9893	Purity: >98%

	Chemical structure of TERT activator-1

For research only, Do not use for Human!

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CAS No.	666699-46-3
Purity	>98%
Formula	C14H12ClF2NO2S
Mol Weight	331.765
Color	white to light yellow
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shim HS, et al. TERT activation targets DNA methylation and multiple aging hallmarks. Cell. 2024 Jul 25;187(15):4030-4042.e13.
CoA	CoA of TERT activator-1

Smiles:	O=S(=O)(NC1=CC=C(F)C(Cl)=C1)C=2C=C(C(F)=C(C2)C)C


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