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Product Information:

Tepotinib Hydrochloride Hydrate

EMD-1214063 is a potent and selective inhibitor of Met with IC50 value of 4 nM for c-Met.

Cat. No.: EX-A394A    Purity: 98+%
Chemical
Chemical structure of Tepotinib Hydrochloride Hydrate


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg565In-stock
1gget quoteIn-stock


CAS No.1946826-82-9
Purity98+%
FormulaC29H31ClN6O3
Mol Weight547.048
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Bladt F, Faden B, Friese-Hamim M, Knuehl C, Wilm C, Fittschen C, Gradler U, Meyring M, Dorsch D, Jaehrling F et al: EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors. Clin Cancer Res, 19(11):2941-2951.

[2]. Bottaro DP, Rubin JS, Faletto DL, Chan AM, Kmiecik TE, Vande Woude GF, Aaronson SA: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991, 251(4995):802-804.
CoACoA of Tepotinib Hydrochloride Hydrate
Smiles:N#CC1=CC=CC(C(C=C2)=NN(CC3=CC=CC(C4=NC=C(OCC5CCN(C)CC5)C=N4)=C3)C2=O)=C1.Cl.O

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