Tenofovir alafenamide fumarate

Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.


Cat. No.: EX-A8377	Purity: >99%

	Chemical structure of Tenofovir alafenamide fumarate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	350	In-stock
500mg	400	In-stock
1g	600	In-stock
5g	1150	In-stock
10g	1750	In-stock
25g	2550	In-stock

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Synonyms	GS 7340 fumarate
CAS No.	379270-38-9
Purity	>99%
Formula	C25H33N6O9P
Mol Weight	592.5381
Color	white to off-white
State	solid powder
Solubility	DMSO : ? 36 mg/mL H2O : ? 25 mg/mL
Shelf Life	>1 years if stored properly
Storage	4°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Babusis D, et al. Mechanism for effective lymphoid cell and tissue loading following oral administration of nucleotide prodrug GS-7340. Mol Pharm. 2013 Feb 4;10(2):459-66. [2]. Ruane PJ, et al. Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults. J Acquir Immune Defic Syndr. 2013 Aug 1;63(4):449-55.
CoA	CoA of Tenofovir alafenamide fumarate

Smiles:	C(=C/C(O)=O)\C(O)=O.C([C@H](OCP(OC1=CC=CC=C1)(N[C@H](C(OC(C)C)=O)C)=O)C)N2C=3C(N=C2)=C(N)N=CN3


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