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Product Information:

Telavancin Hydrochloride

elavancin hydrochloride (TD-6424 hydrochloride) is a bactericidal agent that exhibits inhibitory activity against Staphylococcus aureus. Telavancin hydrochloride inhibits bacterial cell wall synthesis by binding to the lipid-linked N-acetylglucosamine-N-muramyl pentapeptide (with a D-Ala-D-Ala terminus), a peptidoglycan precursor, and blocks the transglycosylation and transpeptidation steps. Telavancin hydrochloride disrupts bacterial membrane barrier function, induces dissipation of bacterial membrane potential, and causes leakage of cytoplasmic ATP and potassium ions, with its activity restricted exclusively to bacterial membranes. Telavancin hydrochloride can be used in research on bacterial infections, central venous catheter-related bloodstream infections, and Gram-positive bacterial pneumonia.

Cat. No.: EX-A7014    Purity: >98%
Chemical
Chemical structure of Telavancin Hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg300In-stock
25mg432In-stock
100mg716In-stock
1gget quoteIn-stock
5gget quoteIn-stock
10gget quoteIn-stock


SynonymsTD 6424
CAS No.560130-42-9
Purity>98%
FormulaC80H107Cl3N11O27P
Mol Weight1792.096
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO 25 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lyseng-Williamson KA, et al. Telavancin. Drugs. 2009;69(18):2607-20.

[2]. Bookstaver PB, et al. Stability and compatibility of antimicrobial lock solutions. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2013 Dec 15;70(24):2185-98.

[3]. Saravolatz LD, et al. Telavancin: a novel lipoglycopeptide. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2009 Dec 15;49(12):1908-14.

CoACoA of Telavancin Hydrochloride

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