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Product Information:

TDP-43-IN-1

TDP-43 ligand-1 is a specific ligand for TDP43, and its Ki value for binding to TDP-43 protein aggregates is 78 nM. TDP-43 ligand-1 can be used in the research of PET imaging probes for TDP-43 proteinopathies.

Cat. No.: EX-A14052    Purity: >98%
Chemical
Chemical structure of TDP-43-IN-1


For research only, Do not use for Human!

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CAS No.3033951-71-9
Purity>98%
FormulaC20H17F2N5OS
Mol Weight413.444
ColorLight yellow to yellow
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, stored under nitrogen; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nicolas Dreyfus, et al. Novel compounds for the diagnosis of tdp-43 proteinopathies. WO2024068948A1. 2024-04-04.

CoACoA of TDP-43-IN-1
Smiles:FC1=C(C=CC(N2CC[C@@H](C2)F)=N1)C3=NC(CCN(C4=CN=CC=C4)C5=O)=C5S3

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