TDI-11055

TDI-11055 is an ENL inhibitor. TDI-11055 blocks the YEATS domain interaction with acylated histones which, in turn, results in the displacement of ENL from the chromatin.


Cat. No.: EX-A11461	Purity: >98%

	Chemical structure of TDI-11055

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	598	In-stock
100mg	898	In-stock
250mg	1526	In-stock
500mg	2475	In-stock
1g	3980	In-stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2657651-10-8
Purity	>98%
Formula	C22H24N6O
Mol Weight	388.4656
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	4℃, protect from light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Liu, Yiman et al. “Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia.” Cancer discovery vol. 12,11 (2022): 2684-2709. doi:10.1158/2159-8290.CD-21-1307
CoA	CoA of TDI-11055

Smiles:	O=C(C1=CC2=C(N(C)N=C2)C=C1)NC3=CC(NC(CN4[C@@H](C)CCC4)=C5)=C5C=N3


		Search