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Product Information:

TC13172

TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2 nM for HT-29 cells .

Cat. No.: EX-A3033    Purity: >98%
Chemical
Chemical structure of TC13172


For research only, Do not use for Human!

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CAS No.2093393-05-4
Purity>98%
FormulaC17H16N4O5S
Mol Weight388.398
Coloroff-white to light yellow
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Bo Yan, et al. Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein.ChemCommun (Camb). 2017 Mar 28;53(26):3637-3640.

CoACoA of TC13172
Smiles:CN1C(=NC2=C1C(=O)N(C)C(=O)N2CC#CC1=CC(O)=CC=C1)S(C)(=O)=O

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