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Product Information:

TC LPA5 4

TC LPA5 4 is a LPA5 (GPR92)-specific non-lipid antagonist. TC LPA5 4 inhibits LPA-induced aggregation of isolated human platelet (LPA5-RH7777 cell line) with an IC50 of 800 nM. TC LPA5 4 inhibits cell proliferation and migration of thyroid cancer cells.

Cat. No.: EX-A6815    Purity: >98%
Chemical
Chemical structure of TC LPA5 4


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg700In-stock
250mg1300In-stock
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CAS No.1393814-38-4
Purity>98%
FormulaC23H23ClN2O3
Mol Weight410.893
Color Light yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO 62.5 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kozian DH, et al. Selective non-lipid modulator of LPA5 activity in human platelets. Bioorg Med Chem Lett. 2012;22(16):5239-5243.

[2]. Zhao WJ, et al. LPAR5 promotes thyroid carcinoma cell proliferation and migration by activating class IA PI3K catalytic subunit p110β. Cancer Sci. 2021;112(4):1624-1632.

CoACoA of TC LPA5 4

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