TC ASK 10

TC ASK 10 (Compound 10) is a potent, selective and orally active apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 of 14 nM. The inhibitory activities of TC ASK 10 towards other representative panel of kinases are less than 50%, except for ASK2 (IC50 of 0.51 μM)[1].


Cat. No.: EX-A14625	Purity: >98%

	Chemical structure of TC ASK 10

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	621	in_stock
250mg	1036	in_stock
500mg	1794	in_stock
1g	2907	in_stock
2g	5149	in_stock

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CAS No.	1005775-56-3
Purity	>98%
Formula	C21H23Cl2N5O
Mol Weight	432.346
Color	White to pink
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Terao Y, et al. Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7326-9.
CoA	CoA of TC ASK 10

Smiles:	CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=CN3C=C(C=CC3=N2)N4C=CN=C4.Cl.Cl


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