TAK-994

Firazorexton hydrate (TAK-994) is an orally active and brain-penetrant orexin type 2 receptor (OX2R) selective agonist. Firazorexton hydrate can promote wakefulness and has the potential to improve narcolepsy-like symptoms in mice .


Cat. No.: EX-A8302	Purity: >98%

	Chemical structure of TAK-994

For research only, Do not use for Human!

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Synonyms	Firazorexton hydrate
CAS No.	2861934-86-1
Purity	>98%
Formula	C22H27F3N2O5S
Mol Weight	488.52
Color	White to off-white
State	solid powder
Shelf Life	>1 years if stored properly
Storage	-20°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Ishikawa T, et al. TAK-994, a Novel Orally Available Brain-Penetrant Orexin 2 Receptor-Selective Agonist, Suppresses Fragmentation of Wakefulness and Cataplexy-Like Episodes in Mouse Models of Narcolepsy. J Pharmacol Exp Ther. 2023 Jun;385(3):193-204.
CoA	CoA of TAK-994

Smiles:	C([C@@H]1N(C(C(C)(C)O)=O)CC[C@@H]1NS(C)(=O)=O)C2=C(F)C(=CC=C2)C3=CC(F)=CC(F)=C3.O


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