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Product Information:

Tagtociclib hydrate

PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).

Cat. No.: EX-A5350A    Purity: >98%
Chemical
Chemical structure of Tagtociclib hydrate


For research only, Do not use for Human!

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SynonymsPF-07104091 hydrate
CAS No.2733575-91-0
Purity>98%
FormulaC19H30N6O5
Mol Weight422.4787
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : ? 100 mg/mL
Shelf Life>2 years if stored properly
Storage4°C, sealed storage, away from moisture and light
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Douglas Carl BEHENNA, et al. Cdk2 inhibitors. WO2020157652A2.

CoACoA of Tagtociclib hydrate
Smiles:O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]

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