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Product Information:

T0080

T0080 is a FPR-1 antagonist. T0080 reduces the cell apoptosis, inhibits ROS production and pro-inflammatory cytokines (TNF-α and IL-1β) from plaque macrophages, which attenuates atherosclerotic progression in ApoE−/− mice.

Cat. No.: EX-A16176    Purity: >98%
Chemical
Chemical structure of T0080


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg292In-stock
10mg472In-stock
25mg792In-stock
50mg1250In-stock
100mg1785In-stock
500mgget quoteIn-stock


CAS No.2785323-68-2
Purity>98%
FormulaC24H22F3N3O3
Mol Weight457.445
ColorWhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, sealed storage, away from light, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Lv J, et al. Formyl peptide receptor 1 signaling exacerbates hemorrhagic transformation following tPA thrombolysis in mice. J Cereb Blood Flow Metab. 2026;46(3):682-694.

[2].Li Y, et al. Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration. Science. 2025;390(6774):eadq1177.

CoACoA of T0080
Smiles:O=C1C2=NNC(C=3C=C(C=CC3O)C)=C2C(C4=CC=C(C=C4)C(F)(F)F)N1C5CCOCC5

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