Sulfo-PDBA-DM4

Sulfo-PDBA-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody agent conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker.


Cat. No.: EX-A9727	Purity: >98%

	Chemical structure of Sulfo-PDBA-DM4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	get quote	Inquire
50mg	get quote	Inquire
100mg	9800	Inquire
500mg	26850	Inquire

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CAS No.	1461704-01-7
Purity	>98%
Formula	C42H60ClN3O15S3
Mol Weight	978.585
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sun X, et al. Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates. Bioconjug Chem. 2017 May 17;28(5):1371-1381.
CoA	CoA of Sulfo-PDBA-DM4

Smiles:	C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCC(SSCCC(S(=O)(=O)O)C(O)=O)(C)C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]


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