STX-478

STX-478 (compound 80) is an oral CNS-penetrant allosteric mutant-selective PI3Kα inhibitor. STX-478 shows robust and durable tumor regression and can be used in cancer research.


Cat. No.: EX-A7997	Purity: >98%

	Chemical structure of STX-478

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	770	in_stock
250mg	1178	in_stock
500mg	1749	in_stock
1g	2616	in_stock
2g	3822	in_stock
5g	7234	in_stock

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Synonyms	STX-478
Synonyms 2	STX-478-101
CAS No.	2883540-92-7
Purity	>98%
Formula	C16H12F5N5O2
Mol Weight	401.2908
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. JR David St Jean, et al. Urea derivatives which can be used to treat cancer. Patent WO2022265993A1.
CoA	CoA of STX-478

Smiles:	NC1=NC=C(C=N1)NC(N[C@H](C2=C(C3=CC(F)=CC(F)=C3O2)C)C(F)(F)F)=O


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