STL1267

STL1267 is a potent and cross-the-blood-brain barrier REV-ERB agonist with a Ki value of 0.16 µM for REV-ERBα. STL1267 shows no cytotoxicity. STL1267 inhibits the gene expression of BMAL1.


Cat. No.: EX-A7373	Purity: >98%

	Chemical structure of STL1267

For research only, Do not use for Human!

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CAS No.	1429024-58-7
Purity	>98%
Formula	C17H11ClN4O
Mol Weight	322.748
Color	White to off-white
State	solid powder
Solubility	DMSO : 25 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Murray MH, et al. Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB. Nat Commun. 2022 Nov 21;13(1):7131.
CoA	CoA of STL1267


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