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Product Information:

STING agonist-4

STING agonist-4 is an stimulator of Interferon Genes (STING) receptor agonist with an apparent inhibitory constant (IC50) of 20 nM. STING agonist-4 is a two symmetry-related amidobenzimidazole (ABZI)-based compound to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function.

Cat. No.: EX-A7825    Purity: >98%
Chemical
Chemical structure of STING agonist-4


For research only, Do not use for Human!

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CAS No.2138300-40-8
Purity>98%
FormulaC34H38N12O4
Mol Weight678.7435
ColorWhite to gray
Statesolid powder
SolubilityDMSO : 1 mg/mL H2O : < 0.1 mg/mL
Shelf Life>2 years if stored properly
Storage -20°C, stored under nitrogen
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ramanjulu JM et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Dec;564(7736):439-443.

CoACoA of STING agonist-4
Smiles:CCN1C(=CC(=N1)C)C(=O)NC2=NC3=C(N2CCCCN4C5=C(C=C(C=C5)C(=O)N)N=C4NC(=O)C6=CC(=NN6CC)C)C=CC(=C3)C(=O)N

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