SSTC3

SSTC3 is a casein kinase 1α (CK1α) activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). SSTC3 exhibits minimal gastrointestinal toxicity compared to other classes of WNT inhibitors .


Cat. No.: EX-A9485	Purity: >98%

	Chemical structure of SSTC3

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	600	in-stock
100mg	900	in-stock
250mg	1450	in-stock
500mg	2150	in-stock
1g	2950	in-stock
2g	4450	in-stock

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CAS No.	1242422-09-8
Purity	>98%
Formula	C23H17F3N4O3S2
Mol Weight	518.531
Color	light yellow to yellow
State	solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li B, et al, Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Sci Signal. 2017 Jun 27;10(485). pii: eaak9916.
CoA	CoA of SSTC3

Smiles:	O=C(NC1=NC(C2=NC=CC=C2)=CS1)C3=CC=C(S(=O)(N(C)C4=CC=C(C(F)(F)F)C=C4)=O)C=C3


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